Assistant Research Officer-Chemistry-2019(071/2015)



Assistant Research Officer-Chemistry

Question Paper Code: 68/2018/OL

Category Code: 071/2015

Medium of Question: English

Date of Test 23-01-2019

Department Ayurveda Medical Education

Question 1 : The Socio-religious organisation ‘The Prarthana Samaj’ was founded by

1. M.G. Ranade

2. Keshab Chandra Sen

3. Raja Ram Mohan Roy

4. Dadoba p. Tarkhadkar Brother Atmaram Pandurang


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4. Dadoba p. Tarkhadkar Brother Atmaram Pandurang

Question 2 : Swami Vivekananda attended the Parliament of religious held at Chicago in _________.

1. 1880

2. 1815

3. 1890

4. 1893


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4. 1893

Question 3 : Indian National Congress Annual Session in 1905 held at Benares was presided by

1. Mrs. Annie Besant

2. Pandit B.N. Dhar

3. Gopala Krishna Gokhale

4. R.C. Dutt


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3. Gopala Krishna Gokhale

Question 4 : The Newspapers, Mahratta and Keseri were published by

1. Tilak

2. S. Subramanian Iyer

3. Annie Besant

4. Birendra Ghosh


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1. Tilak

Question 5 : Hindustan Socialist Republican Association (HSRA) was founded under the leadership of _____________

1. Shyamji Krishna Varma

2. Khudiram Bose

3. V.D. Savar

4. Chandra Shekhar Azad


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4. Chandra Shekhar Azad

Question 6 : The Asiatic Society of Bengal was founded by

1. David Hare

2. Sir. William Jones

3. Macaulay

4. Sir. Charles Wood


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2. Sir. William Jones

Question 7 : Jalian Wala Bagh tragedy occurred in

1. 1922

2. 1918

3. 1925

4. 1919


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4. 1919

Question 8 : The Karakoram Mountain range is situated in the state of

1. Rajasthan

2. Gujarat

3. Jammu and Kashmir

4. Orissa


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3. Jammu and Kashmir

Question 9 : Which of the following countries share the largest border length with India?

1. China

2. Bangladesh

3. Nepal

4. Sreelanka


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2. Bangladesh

Question 10 : The famous hill station ‘Kodai Kanal’ lies in ____________.

1. Western Ghats

2. Palani hills

3. Nilgiri hills

4. Cardamom hills


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2. Palani hills


Question 11 : The film “Ayya Vazhi” is based on the life of

1. Ayyankali

2. Kumara Guru

3. Ayya Vaikundar

4. Sree Narayana Guru


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3. Ayya Vaikundar

Question 12 : The book Jathi Kummi was written by

1. Dr. Palpu

2. Mannathu Padmanabhan

3. Pandit Kuruppan

4. Ayya Vaikundar


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3. Pandit Kuruppan

Question 13 : SNDP Yogam was founded in

1. 1903

2. 1905

3. 1915

4. 1935


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1. 1903

Question 14 : The Social reformer Kunjan Pillai is known as

1. Mannathu Padmanabhan

2. Chattampi Swamikal

3. V.T. Bhattathirippad

4. Ayya Vaikundar


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2. Chattampi Swamikal

Question 15 : Who is known as ‘The father of Muslim renaissance?’

1. Chalilkathu Kunjahammad Haji

2. Vaikom Abdul Khadar Moulavi

3. Abdulla Musaliyar

4. Hamadani Tangal


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2. Vaikom Abdul Khadar Moulavi

Question 16 : Who is appointed as the new chairman of ISRO?

1. K. Radhakrishnan

2. G. Madhavan Nair

3. A.S. Kiran Kumar

4. Dr. K. Sivan


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4. Dr. K. Sivan

Question 17 : The film that received the Oscar Academy Award for the best film in 2018?

1. The Shape of Water

2. Get out

3. Call me by your name

4. Darkest hour


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1. The Shape of Water

Question 18 : Which country won Sultan Azlan Shah Cup 2018?

1. England

2. South Korea

3. Argentina

4. Australia


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4. Australia

Question 19 : Who was awarded the Sarswati Samman of 2017?

1. Harivansh Rai Bachan

2. Ramakanta Rath

3. Sitanshu Yashas Chandra

4. Vijay Tendulkar


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3. Sitanshu Yashas Chandra

Question 20 : India-France joined navel exercise is called

1. Varuna Exercise

2. Malabar Exercise

3. Indra

4. Sinbex


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1. Varuna Exercise


Question 21 : How many significant figures are present in the number 0.0025?

1. 5

2. 4

3. 2

4. 6


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3. 2

Question 22 : The expansion of DSC is

1. Differential Scanning Calorimetry

2. Differential Scanning Coulometry

3. Differential Spinning Calorimetry

4. Differential Spinning Coulometry


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1. Differential Scanning Calorimetry

Question 23 : The property measured in TGA is

1. Change in weight

2. Rate of change in weight

3. Heat evolved or absorbed

4. Change in temperature


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1. Change in weight

Question 24 : In Freundlich Adsorption Isotherm the value of 1/n is

1. 1 in case of physical adsorption

2. 1 in case of chemical adsorption

3. Between 0 and 1 in all cases

4. Between 0 and 2 in all cases


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3. Between 0 and 1 in all cases

Question 25 : If `((x)/(m))` is the mass of adsorbate per unit mass of adsorbent. `p` is the pressure of adsorbate gas and `a` and `b` are constants, which of the following represents “Langmuir” adsorption isotherm?

1. `log((x)/(m)) = log((a)/(b)) + (1)/(a)logp`

2. `(x)/(m)=(b)/(a)+(1)/(ap)`

3. `(x)/(m)=(1+bp)/(ap)`

4. `(1)/((x/m))= (b)/(a)+(1)/(ap)`


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4. `(1)/((x/m))= (b)/(a)+(1)/(ap)`

Question 26 : The molecule which is IR inactive but Raman active is

1. `”N_2″`

2. `”HCl”`

3. `”SO_2″`

4. Protein


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1. `”N_2″`

Question 27 : The ESR of Naphthalene radical anion consists of

1. 15 lines

2. 25 lines

3. 30 lines

4. 40 lines


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2. 25 lines

Question 28 : What is the main factor on which chemical shift depends in Mossbauer spectrum?

1. Electron density

2. Transition energy

3. Intensity of light

4. All of these


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1. Electron density

Question 29 : The confinement in a Quantum wire is

1. 0 D

2. 2 D

3. 1 D

4. 3 D


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2. 2 D

Question 30 : The expansion of ‘SPR’ is

1. Surface Plasmon Resonance

2. Surface Proton Resonance

3. Structural Plasmon Resonance

4. Structural Proton Resonance


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1. Surface Plasmon Resonance


Question 31 : Quantum dots are

1. 1 dimensional

2. 0 dimensional

3. 3 dimensional

4. 2 dimensional


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2. 0 dimensional

Question 32 : Dip-Pen nanolithography works with the help of

1. TEM

2. SEM

3. AFM

4. EDAX


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3. AFM

Question 33 : The chemical bonds of carbon nanotube is composed of

1. `”sp”` bonds

2. `”sp^2″` bonds

3. `”sp^3″` bonds

4. none of these


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2. `”sp^2″` bonds

Question 34 : The polar groups in cation-exchange resins are

1. acidic

2. basic

3. neutral

4. none of these


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1. acidic

Question 35 : In Chromatography `R_f` value

1. `(text {Distance moved by the solute})/(text {Distance moved by the solvent})`

2. `(text {Distance moved by the solvent})/(text {Distance moved by the solute})“ `

3. `(text {Distance moved by the solute})/(text {Distance moved by the solution})`

4. `(text {Distance moved by the solution})/(text {Distance moved by the solute})`


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1. `(text {Distance moved by the solute})/(text {Distance moved by the solvent})`

Question 36 : In which of the following techniques the mobile phase is a gas?

1. HPLC

2. GC

3. TLC

4. Ion-Exchange Chromatography


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2. GC

Question 37 : The process of recovery of the constituents from the chromatogram is called

1. Dilution

2. Elution

3. Eluent

4. Recoveration


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2. Elution

Question 38 : Iron-sulphur clusters in biological systems are involved in

1. proton transfer

2. atom transfer

3. group transfer

4. electron transfer


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4. electron transfer

Question 39 : The metal present in carbonic anhydrase is

1. Mn

2. Zn

3. Mg

4. Cu


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2. Zn

Question 40 : What is not true about Ferredoxins?

1. Involved in oxidation of “`”{NH_3}”`

2. Generate `”{H_2}”` from acid solution

3. Reduction potential is from 0 to +0.5 V

4. It is Fe-S protein


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3. Reduction potential is from 0 to +0.5 V


Question 41 : Cytochromes acts as

1. Two electron transfer agents

2. One electron transfer agents

3. Multi electron transfer agents

4. None of these


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2. One electron transfer agents

Question 42 : Nitrogenase contains

1. Fe, Mo

2. Mg, Fe

3. Fe, Zn

4. Fe, Cu


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1. Fe, Mo

Question 43 : The interior of β-cyclodextrin is

1. hydrophobic

2. hydrophilic

3. hydrophobic and hydrophilic

4. none of these


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1. hydrophobic

Question 44 : γ-cyclodextrin (γ-CD) contains

1. eight glucose units

2. seven glucose units

3. six glucose units

4. five glucose units


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1. eight glucose units

Question 45 : Calixarenes are synthetic compounds which are made by cyclooligomerization of

1. Amines

2. Phenols

3. Ketones

4. Amides


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2. Phenols

Question 46 : Macromolecules which are made up of two or more rings held together as links in a chain are called

1. Catenanes

2. Rotaxanes

3. Cyclodextrins

4. Calixarenes


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1. Catenanes

Question 47 : ‘Zeolites’ is a broad term used to describe a family of minerals called

1. Trisilicates

2. Pentasilicates

3. Tetrasilicates

4. Tectosilicates


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4. Tectosilicates

Question 48 : “Clayan” is a non-metallic oxidative green reagent composed of

1. Clay Supported Ammonium Nitrate

2. Clay Supported Aluminium Nitrate

3. Clay Supported Ammonium Nitrite

4. Clay Supported Aluminium Nitrite


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1. Clay Supported Ammonium Nitrate

Question 49 : The phosphorescence is due to the transition from

1. Singlet → Singlet

2. Singlet → Triplet

3. Triplet → Singlet

4. Triplet → Triplet


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3. Triplet → Singlet

Question 50 : The quantum yield of photochemical chlorination of methane is

1. < 1

2. 1

3. > 1

4. 0


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3. > 1


Question 51 : Saturated solution if `”KNO_3″` is used to make ‘Salt bridge’ becomes

1. Velocity of `”K^+”` is greater than that of `”NO^-_3″`

2. Velocity of `”NO^-_3″` is greater than that of `”K^+”`

3. Velocity of `”K^+”` and `”NO^-_3″` are nearly the same“

4. `”KNO_3″` is highly soluble in water


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3. Velocity of `”K^+”` and `”NO^-_3″` are nearly the same“

Question 52 : Which of the following decreases with increase in concentration?

1. Conductance

2. Specific conductance

3. Equivalent conductance

4. Molar conductance


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2. Specific conductance

Question 53 : Phosphofructokinase 2, a bifunctional enzyme can regulate glycolytic pathway. Which of the following statement is correct regarding this enzyme?I.Kinase activity is active in their phosphorylated form.II. Kinase activity is active in their dephosphorylated form.III. Phosphatase activity is active in their phosphorylated form.IV. Phosphatase activity is active in their dephosphorylated form

1. I & III

2. I & IV

3. II & III

4. II & IV


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3. II & III

Question 54 : Aspartate transcabamoylase is an example of allosteric enzyme and it contains 6 regulatory and 6 catalytic subunits. Which of the following is correct about his enzyme?I.ATP is an allosteric activator of this enzyme.II. ATP is an allosteric inhibitor of this enzyme.III. The subunit composition of ATCase is `”3C_22R_3″`.IV. The subunit composition of ATCase is `”2C_33R_2″`

1. I and III

2. I and IV

3. II and III

4. II and IV


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2. I and IV

Question 55 : Gluconeogenesis pathway can produce glucose from noncarbohydrate precursors. This pathway occurs in which of the following sub cellular compartment/s?

1. Cytosol

2. Cytosol and mitochondria

3. Cytosol and endoplasmic reticulum

4. Cytosol, mitochondria and endoplasmic reticulum


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4. Cytosol, mitochondria and endoplasmic reticulum

Question 56 : Thymidylate synthase catalyse the conversion of dUMP to dTMP, which of the following donate the methyl group?

1. Methyl THF

2. Methylene THF

3. Formyl THF

4. SAM


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2. Methylene THF

Question 57 : Suppose the number of carbon rings in an `”F_0/F_1″` ATP synthase is 12. Then the value of P/O ratio for NADH, `”H^+”` and `”FADH_2″` respectively are

1. 2 and 1.2

2. 2.5 and 1.5

3. 3 and 2

4. 1.5 and 2.5


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1. 2 and 1.2

Question 58 : Beta oxidation of a 20C saturated fatty acid to `”CO_2″` generate which of the following number of reductants?

1. 8 NADH, `”H^+”` and 8 `”FADH_2″`

2. 9 NADH, `”H^+”` and 9 `”FADH_2″`

3. 10 NADH, `”H^+”` and 10 `”FADH_2″`

4. 7 NADH, `”H^+”` and 7 `”FADH_2″`


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2. 9 NADH, `”H^+”` and 9 `”FADH_2″`

Question 59 : Mixed inhibition and non-competitive inhibition are of two types of reversible inhibition. Which of the following is correct related to these inhibitions?

1. In both mixed inhibition and non-competitive inhibition `”V_m_a_x”` decreases and Km increases

2. In mixed inhibition `”V_m_a_x”` decreases and Km increases, in non-competitive inhibition `”V_m_a_x”` decreases and Km unchanged

3. In both mixed inhibition and non-competitive inhibition `”V_m_a_x”` and Km decreases

4. In mixed inhibition `”V_m_a_x”` decreases and Km decreases, in non-competitive inhibition `”V_m_a_x”` decreases and Km increases


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2. In mixed inhibition `”V_m_a_x”` decreases and Km increases, in non-competitive inhibition `”V_m_a_x”` decreases and Km unchanged

Question 60 : Which of the following RNA molecule is NOT a ribozyme?

1. 28S rRNA

2. 5S rRNA

3. RNA part of RNase P

4. Hammer head RNA


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2. 5S rRNA


Question 61 : Carbonic anhydrase enzyme catalyse the production of carbonic acid from water and `”CO_2″` . Which of the following is correct related to this enzyme?

1. Carbonic anhydrase decreases the `”pK_a”` value of water

2. Carbonic anhydrase increases the `”pK_a”` value of water

3. `”K^+”` is the cofactor of carbonic anhydrase

4. `”Ca^2^+”` is the cofactor of carbonic anhydrase


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1. Carbonic anhydrase decreases the `”pK_a”` value of water

Question 62 : Which of the following is the ratio of phospholipid : sphingomyelin : cholesterol in a normal eukaryotic cell plasma membrane?

1. 1:1:1

2. 1.5:0.5:1

3. 0.5:1.5:1

4. 1:0.5:1.5


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2. 1.5:0.5:1

Question 63 : The absorption of ultraviolet (UV) light (the absorbance at 280 nm) is often used as a measure of protein concentration. The R-groups of which amino acids contribute most to absorption of 280 nm light?

1. Ser, Thr, Cys

2. Lys, Arg, His

3. Trp, Tyr, Phe

4. Ser, Ala, Glu


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3. Trp, Tyr, Phe

Question 64 : In a eukaryotic cell plasma membrane, different phospholipid preferentially localized to either cytosolic side or exoplasmic side. Which of the following is the correct orientation of phospholipids like phosphatidyl choline and phosphatidyl inositol in cytosolic and exoplasmic side?

1. Both are cytosolic

2. Both are exoplasmic

3. Phosphatidyl choline is localized to cytosolic and phosphatidyl inositol is localized to exoplasmic

4. Phosphatidyl inositol is localized to cytosolic and phosphatidyl choline is localized to exoplasmic


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4. Phosphatidyl inositol is localized to cytosolic and phosphatidyl choline is localized to exoplasmic

Question 65 : Which of the following cyclin is responsible to activate CDK4 and CDK6 to pass the cell cycle from G1 phase?

1. Cyclin A

2. Cyclin B

3. Cyclin D

4. Cyclin E


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3. Cyclin D

Question 66 : Which of the following transposons is an example of non autonomous transposon?

1. Ac elements in maize

2. Ds elements in maize

3. P elements in drosophila

4. IS elements in bacteria


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2. Ds elements in maize

Question 67 : `”Na^+/K^+”` pump utilize ATP hydrolysis to pump `3″Na^+”` to the extracellular side and 2 `”K^+”` to the intracellular side and generate an electric potential to the cell. This pump belong to

1. F type pump

2. V type pump

3. P type pump

4. ABC type pump


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3. P type pump

Question 68 : Which monomeric G proteins are involved in the formation of filopodium, lamellipodium and stress fibers?

1. Filopodium – cdc42, Lamellipodium – Rac, Stress fibers – Rho

2. Filopodium – Rac, Lamellipodium – cdc42, Stress fibers – Rho

3. Filopodium – Rho, Lamellipodium – Rac, Stress fibers – cdc42

4. None of the above


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1. Filopodium – cdc42, Lamellipodium – Rac, Stress fibers – Rho

Question 69 : Apoptosis (programmed cell death) executed by the action of caspase enzyme in intrinsic and extrinsic pathway of apoptosis. Which of the following caspase is involved in intrinsic pathway of apoptosis?

1. Proteolytic cleavage of procaspase to caspase 9

2. Dimerisation of procaspase to caspase 9

3. Proteolytic cleavage of procaspase to caspase 8

4. Dimerisation of procaspase to caspase 8


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2. Dimerisation of procaspase to caspase 9

Question 70 : Replication in both prokaryotes and eukaryotes occur only in 5′ → 3′ direction. Which of the following reason for that?

1. Primer addition is not possible

2. Okazaki fragments not possible

3. Leading strand synthesis is not possible

4. Proofreading is not possible


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4. Proofreading is not possible


Question 71 : Which of the following protein are involved in the development of dorsal side of the embryo?

1. Decapentaplegic and tolloid

2. Dorsal and fgf 8

3. Bicoid and hunchback

4. Nanos and Caudal


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1. Decapentaplegic and tolloid

Question 72 : Which of the following photosystem locate in the appressed (stalked) portion of thylakoid membrane?

1. Photosystem I

2. Photosystem II

3. Cyt bf complex

4. Light harvesting complex I


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2. Photosystem II

Question 73 : Which of the following RNA polymerase is involved in the synthesis of RNA part of `”U_6″` spliceosome?

1. RNA polymerase I

2. RNA polymerase II

3. RNA polymerase III

4. RNA polymerase IV


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3. RNA polymerase III

Question 74 : Plant secondary metabolite flavonoids are derived from the amino acid phenylalanine. Which of the following is the precursor of flvaonoids synthesizing pathway?

1. Chorismate

2. Enol pyruvate shikimate pathway

3. Prephenate

4. Chalcone


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4. Chalcone

Question 75 : Which of the following amino acid use a single codon for the translation of proteins in humans?

1. Alanine

2. Histidine

3. Valine

4. Tryptophan


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4. Tryptophan

Question 76 : Which of the following secondary metabolite is used as an anticancer drug derived from the bark of Yew trees?

1. Camptothecin

2. Taxol

3. Cochicine

4. Vincristine


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2. Taxol

Question 77 : Which of the following plant hormone is responsible for the formation of quiescent centre in root apical meristem?

1. Auxin

2. Cytokinin

3. Gibberlin

4. Ethylene


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1. Auxin

Question 78 : Which of the following operon use its regulatory gene product as a transcriptional activator and repressor?

1. Lac operon

2. Galactose operon

3. Arabinose operon

4. Tryptophan operon


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3. Arabinose operon

Question 79 : Which of the following compound is elevated in response to plant experience a water stress?

1. Myoinositol

2. Galactinol

3. Raffinose

4. Proline betaine


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4. Proline betaine

Question 80 : Which of the following repair system use blue light energy to correct the errors?

1. Direct repair

2. Nucleotide excision repair

3. Mismatch repair

4. Recombination repair


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1. Direct repair


Question 81 : Glycoproteins

1. contain oligosaccharides linked to the side chain of lysine or histidine residues

2. contain oligosaccharides linked to the side chain of asparagine, serine, or threonine residues

3. bind to liver cell-surface receptors that recognize sialic acid residues

4. are mostly cytoplasmic proteins


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2. contain oligosaccharides linked to the side chain of asparagine, serine, or threonine residues

Question 82 : Which of the following is an example of a restriction site that shows two-fold rotational symmetry?

1. ATTA

2. ATAATA

3. ATAT

4. ATTTTA


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3. ATAT

Question 83 : A deficiency in which of the following amino acids will result in the negative nitrogen balance, even though the diet may contain a large amount of protein

1. Alanine

2. Serine

3. Glutamate

4. Tryptophan


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4. Tryptophan

Question 84 : Which of the following binding interactions is likely to be the most important initial interaction when a drug enters a binding site?

1. Van der Waals interactions

2. Hydrogen bond

3. Ionic

4. Induced dipole-dipole interactions


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3. Ionic

Question 85 : During photosynthesis, which of the followings acts as a reservoir for hydrogen ions?

1. Cristae

2. Stroma

3. Thylakoid space

4. Matrix


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3. Thylakoid space

Question 86 : Maple syrup urine disease is a deficiency of which amino acid degradative pathway?

1. Tyrosine

2. Leucine

3. Tryptophan

4. Arginine


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2. Leucine

Question 87 : The light microscope that is often used to view internal structures of living cells without staining is

1. Dark-field microscope

2. Bright-field microscope

3. Fluorescence microscope

4. Phase-contrast microscope


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4. Phase-contrast microscope

Question 88 : Which of the following medium is used to select the heterokaryon hybridoma cell in hybridoma technology?

1. Hydroxy urea, aminopterine, thymidine

2. Hypoxanthine, acetaminophen, thymidine

3. Hypoxanthine, aminopterine, thiourea

4. Hypoxanthine, aminopterine, thymidine


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4. Hypoxanthine, aminopterine, thymidine

Question 89 : An example of inactivated exotoxin

1. Cholera vaccine

2. Rabies vaccine

3. Hepatitis B vaccine

4. Rubella vaccine


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3. Hepatitis B vaccine

Question 90 : Polyacrylamide and agarose gel electrophoresis separate nucleic acids based primarily on their

1. Length

2. Ratio of mass/charge

3. (G+C)/(A+T) content

4. Organismal origin


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1. Length



Assistant Research Officer-Chemistry

Question Paper Code: 68/2018/OL

Category Code: 071/2015

Assistant Research Officer-Chemistry

Medium of Question: English

Date of Test 23-01-2019

Department Ayurveda Medical Education

Alphacode A

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